Peripapillary atrophy (PPA) is a clinical finding associated with chorioretinal thinning and disruption of the retinal pigment epithelium (RPE) in the area surrounding the optic disc. It is non-specific and can occur in both benign and pathologic conditions, including glaucoma 1 and high myopia 2.
- What is papillary atrophy?
- What causes atrophy of the optic nerve?
- What does Peripapillary mean?
- Can optic nerve atrophy be treated?
- Is Peripapillary atrophy common?
- How do you get optic atrophy?
- Can Peripapillary atrophy cause an enlarged blind spot?
- What is the Peripapillary area?
- What does eye atrophy mean?
- What causes optic nerve atrophy?
What is papillary atrophy?
Papillary atrophy is an important finding characteristics of vitamin B 12 deficiencyvitamin B 12 deficiencyVitamin B12 deficiency has 3 primary etiologies: Autoimmune: Pernicious anemia is an autoimmune condition in which antibodies to intrinsic factor are produced. Anti-intrinsic factor antibodies bind to and inhibit the effects of intrinsic factor, resulting in an inability of B12 to be absorbed by the terminal ileum.https://www.ncbi.nlm.nih.gov › books › NBK441923Vitamin B12 Deficiency - StatPearls - NCBI Bookshelf. Tongues with vitamin B 12 deficiency have a smooth, glossy appearance with a red or pink background.
What causes atrophy of the optic nerve?
What causes optic nerve atrophy? ONA causes include: tumor, trauma, decreased blood supply (ischemia) or oxygen supply (hypoxia) causing swelling, hereditary, hydrocephalus, toxins, infection, and rare degenerative disorders. Onset can be from birth through adulthood.
What does Peripapillary mean?
: situated around the optic papilla.
Optic Atrophy
Can optic nerve atrophy be treated?
Treatment. Damage from optic nerve atrophy cannot be reversed. The underlying disease must be found and treated. Otherwise, vision loss will continue.
Is Peripapillary atrophy common?
Chorioretinal atrophy surrounding the optic disc (known as either peri- or parapapillary atrophy) is a relatively common clinical finding.
How do you get optic atrophy?
Optic atrophy can occur in cases where the optic nerve did not develop properly. It may also result from inflammation of the optic nerve or from glaucoma when the pressure inside the eye remains too high. In unusual cases, poisons, vitamin deficiencies, or tumors may be responsible.
Optic Atrophy - Disc Morphology
Can Peripapillary atrophy cause an enlarged blind spot?
Subjects with high myopia from axial elongation usually develop a crescent-shaped region of peripapillary temporal atrophy, sometimes with tilting of the optic disc. There are no photoreceptors in this atrophic zone, and partial or complete absence of other retinal layers. Consequently, the blind spot becomes enlarged.
What is the Peripapillary area?
The peripapillary region was defined as a 700-μm-wide elliptical annulus extending from the optic disc boundary. An en face angiogram of the retinal circulation was obtained by the maximum flow (decorrelation value) projection from the inner limiting layer to retinal epithelial pigment.
Peripapillary Retinal Layers – Video Abstract [Id 150617]
What does eye atrophy mean?
Optic atrophy is a condition that affects the optic nerve, which carries impulses from the eye to the brain. (Atrophy means to waste away or deteriorate.) There is no effective treatment for this condition.
What causes optic nerve atrophy?
What causes optic nerve atrophy? ONA causes include: tumor, trauma, decreased blood supply (ischemia) or oxygen supply (hypoxia) causing swelling, hereditary, hydrocephalus, toxins, infection, and rare degenerative disorders. Onset can be from birth through adulthood.